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CO2 Renew 5-Pack — five 10mL tubes CO2 Renew tube in hand CO2 Renew 10mL single tube detail Five CO2 Renew 10mL tubes laid out flat
Entry Point — Patented At-Home Carboxytherapy

CO2 Renew 5-Pack

Clinical carboxytherapy. In your medicine cabinet.

$99 5-Pack · under $3 per treatment

Subscribe & Save 5% — auto-delivery every 4 weeks

Comparable carboxytherapy sessions: $90–$290. CO2 Renew 5-Pack: $3 per tube.

Five tubes. $99. Under $3 per treatment. The only patented at-home CO₂ therapy paste. Same Bohr Effect clinics charge $90–$290 to deliver — now shelf-stable and yours to apply.

Free US shipping · 30-day guarantee · Subscribe & Save 5%

If you don't feel the warmth on application one, send the unused tubes back.

If you don't feel the warmth on application one, send the unused tubes back.

Patented Formula

First device-free CO2 therapy

20-Minute Sessions

Apply · wait · rinse

Peer-Reviewed Mechanism

Bohr Effect · carboxytherapy

Free US Shipping

30-day guarantee

Patented formula

20-minute sessions

Peer-reviewed mechanism

Free US shipping

30-day guarantee

Three Ways to Start

Three ways to start. One mechanism.

CO2 Renew 10mL single tube

Try it once

CO2 Renew 10mL — $29

One tube. Two to three treatments. A clean way to feel the warmth, see the flush, and decide for yourself.

Add single tube — $29
★ Recommended
CO2 Renew 5-pack of 10mL tubes

Best Value

CO2 Renew 5-Pack — $99

Five 10mL tubes. Under $3 per treatment. Enough for a month of spot therapy, a travel kit, or a starter for the whole household. Start here — best value for most.

Subscribe & Save 5%

Add 5-Pack — $99
CO2 Renew 100mL professional tube

Clinical-grade refill

CO2 Renew 100mL — $189

The full-size professional tube. ~25–30 facial applications or 15–20 body applications. The version used in clinics.

Add 100mL — $189

The Only Patented At-Home Carboxytherapy

Not a serum. Not a cream. A therapy.

You've tried the serums. You've hit the ceiling of what topicals can do. CO2 Renew is a different category. It's topical carboxytherapy — the therapy Japanese cosmetic clinics and European rehab centers have used for decades. Now in a paste you apply at home.

Here's what happens on your skin. The paste releases CO₂ through the skin. Local CO₂ rises. Your hemoglobin lets go of the oxygen it's already carrying. That oxygen reaches the tissue underneath. Blood flow opens up. Repair starts. You feel a gentle warmth. The skin flushes. Then it settles.

One paste. One physiological mechanism. Dozens of applications.

The Mechanism

One mechanism. Three ways it works.

Oxygen, delivered where it's needed.

Your blood is already ~97% oxygen-saturated. The question isn't supply. It's delivery. Raise local CO₂ and hemoglobin lets oxygen go — straight into the tissue. That's the Bohr Effect. It's how your muscles pull oxygen during exercise. CO2 Renew borrows the same signal and puts it on your skin.

Christian Bohr, 1904. See also Nybo & Rasmussen, 2007.

The skin repairs itself faster.

Repair needs circulation. Transcutaneous CO₂ opens the tiny vessels under your skin. More blood reaches the tissue. More oxygen reaches the cells doing the repair work. In studies on the hardest-to-heal patients, that microvascular boost showed up clearly. A clinical trial in healthy adults confirmed the paste's safety and efficacy.

Transcutaneous CO₂ for diabetic foot ulcers; Exploratory clinical trial of carbon dioxide paste.

Circulation you can measure.

Thermal imaging picks up the change after one dry CO₂ session. Peripheral circulation goes up. The same signal quiets local inflammation. Muscle tissue recovers faster after stress.

Sakai et al. — dry CO₂ bathing; Transcutaneous CO₂ accelerates muscle injury repair (rat model).

What Compounds

Your first use, you'll feel it. A month in, you'll see it.

Most people notice a subtle glow the first time. That's circulation opening up. Benefits compound with use. At three times a week, early users tell us they see tone and clarity shift inside the first month.

Start the 5-pack — $99
Skin before and after consistent CO2 Renew use — visible glow and tone improvement.

Use Cases

Three use cases. Same tube.

Post-workout spot therapy

Apply to the calf that won't settle, the shoulder that's barking, the low back that stiffened on the drive home. 20 minutes. Rinse.

Acute flare-ups

The tweak you feel at hour 36 after a heavy session. Circulation is the signal your tissue is waiting for.

Chronic joint areas

Knees, elbows, wrists. Comfortable enough for daily use.

No device. No setup.

Comfortable at skin temperature. Open and apply — that's the whole setup.

Face & neck

Apply after cleansing, before treatment serums. Works beneath the surface, not on top of it.

Post-procedure

Peels, microneedling, laser. CO2 Renew supports the repair window when circulation matters most.

Skin cells, better fed

CO₂ opens the small vessels under your skin. More oxygen reaches the cells that make collagen. Cells that get oxygen heal faster and look healthier. This is the signal behind clinical carboxytherapy.

Layers with your routine

Layers with your existing routine. Doesn't replace it.

TSA-friendly

10mL tubes. Toss five in a Dopp kit. No device. No electricity.

On-road recovery

The race you flew to. The tournament weekend. The hotel-room hamstring.

Shelf-stable

Store at room temperature. Open when you need it.

Fits in your bag

The recovery tool that goes where you go. No charger. No case. Just tubes.

How to Use

Simple enough for tonight.

Applying CO2 Renew paste to skin
1

Apply

Spread a thin, even layer on clean, dry skin. The target area: face, joints, or muscle.

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20-minute wait frame
2

Wait 20 minutes

Feel the gentle warmth as circulation opens. Read. Scroll. Breathe.

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Rinse frame
3

Rinse

Warm water. Follow with your regular serums or moisturizer. Resume your day.

Recommended frequency: 3× per week for compounding results.

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Ross Schilling, founder of AEIR

From Ross — Founder, DC

I built the paste because I can't physically treat everyone.

I'm a chiropractor. A biology degree sits in a drawer somewhere. For the last decade I've been treating athletes and patients with transcutaneous CO₂. It works. And the research behind it is older and deeper than most people realize.

The suit is the clinical experience. But one clinician sees only so many patients a week. The paste scales the mechanism. One tube in a medicine cabinet reaches people I could never treat in person.

Under three dollars a treatment. No device. Same Bohr Effect. That's what I built. — Ross

Meet Ross →

Reviews

What people notice first.

The Complete Recovery Day

Paste for the spot. Suit for the system.

The paste gives you targeted therapy exactly where you need it. The Flex Kit creates a full-body CO₂ environment for a 20–30 minute systemic recovery session. Same mechanism, different scale. Together, they cover the day.

Explore the Flex Kit — $2,799
CO2 Renew paste and AEIR CO2 Flex Kit — targeted and full-body therapy, same mechanism.

Questions

CO2 Renew — answered.

Creams hydrate and deliver ingredients to the surface. CO2 Renew is carboxytherapy — it drives a physiological mechanism (the Bohr Effect) that releases oxygen from hemoglobin into the tissue beneath the skin. Different category, different result.
Yes and yes. CO2 Renew is the only patented at-home carboxytherapy paste. It uses 6 food-grade ingredients, no parabens, and is shelf-stable for 3 years. A clinical trial in healthy adults confirmed its safety and efficacy. Patch-test a small area first if your skin is sensitive.
Each 10mL tube delivers 2–3 targeted treatments. The 5-pack covers 10–15 sessions, depending on application size. At three treatments per week, the 5-pack lasts roughly a month.
Room temperature. Shelf-stable. Unopened tubes are stable until the printed expiry; opened tubes should be used within 90 days.
The paste uses 6 food-grade ingredients — safe enough for kids, pregnant women, and older skin. For use under 18, talk to your clinician first.
Yes, it's comfortable enough for daily use. For cosmetic goals, three times per week is the optimal frequency in most protocols. For acute spot recovery, use as needed.
Auto-delivery every 4 weeks. 5% off every shipment. No contract — pause, skip, or cancel anytime.
30-day satisfaction guarantee on unopened tubes. Opened tubes are non-returnable for hygiene reasons; contact us if there's a quality issue and we'll make it right.
Most users feel the warmth and subtle flush after the first application. That's circulation opening. Cosmetic benefits (tone, clarity) compound over 2–4 weeks at three times per week. For muscle and joint use, most report relief inside the first few sessions.
Yes. Apply CO2 Renew as a treatment step, then rinse, then layer your regular routine. It does not replace your actives — it works beneath them.

Save 5% Every Shipment

Subscribe & Save — 5% off, delivered every 4 weeks.

Auto-renew your 5-pack or 100mL. Skip, pause, or cancel anytime. No contract.

CO2 Renew packaging — clinical carboxytherapy paste.

Feel the warmth. See the flush. Decide for yourself.

30-day satisfaction guarantee. Under $3 a treatment.